The Evolution & Medicine Review

Evolution in Health and Medicine: PNAS supplement published

This Supplement includes 18 open access papers from an April, 2009  Sackler Colloquium at the National Academy of Sciences: Evolution in Health and Medicine Sackler Colloquium

Citation: Evolution in Health and Medicine, PNAS, Vol 107 (suppl 1), 1691-1808, 2010.

Links to the papers are below.  The complete issue in one pdf is here.PNAS-EvMedIssueComplete- pages 1691-1799 (2010) An overview of recommendations for educating medical professionals is here.

Stephen C. Stearns,  Randolph M. Nesse,  Diddahally R. Govindaraju,  and Peter T. Ellison

Evolutionary perspectives on health and medicine

This article provides an overview of the main issues and the papers in the  Supplement

PNAS 2010 107:1691–1695; doi:10.1073/pnas.0914475107

For a related article with recommendations for medical education, click here.

Benjamin M. Althouse,  Theodore C. Bergstrom, and Carl T. Bergstrom

A public choice framework for controlling transmissible and evolving diseases

PNAS 2010 107:1696–1701; published online before print December 14, 2009, doi:10.1073/pnas.0906078107

Gilbert S. Omenn

Evolution and public health

PNAS 2010 107:1702–1709; published online before print December 4, 2009, doi:10.1073/pnas.0906198106

Gil Atzmon, Miook Cho, Richard M. Cawthon, Temuri Budagov, Micol Katz, Xiaoman Yang, Glenn Siegel, Aviv Bergman, Derek M. Huffman, Clyde B. Schechter, Woodring E. Wright, Jerry W. Shay, Nir Barzilai, Diddahally R. Govindaraju, and Yousin Suh

Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians

PNAS 2010 107:1710–1717; published online before print November 13, 2009, doi:10.1073/pnas.0906191106

Caleb E. Finch

Evolution of the human lifespan and diseases of aging: Roles of infection, inflammation, and nutrition

PNAS 2010 107:1718–1724; published online before print December 4, 2009, doi:10.1073/pnas.0909606106

Steven A. Frank

Somatic evolutionary genomics: Mutations during development cause highly variable genetic mosaicism with risk of cancer and neurodegeneration

PNAS 2010 107:1725–1730; published online before print September 23, 2009, doi:10.1073/pnas.0909343106

Bernard Crespi, Philip Stead, and Michael Elliot

Comparative genomics of autism and schizophrenia

PNAS 2010 107:1736–1741; published online before print December 1, 2009, doi:10.1073/pnas.0906080106

Edward C. Holmes

The comparative genomics of viral emergence

PNAS 2010 107:1742–1746; published online before print October 26, 2009, doi:10.1073/pnas.0906193106

Adam Eyre-Walker

Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies

PNAS 2010 107:1752–1756; published online before print January 19, 2010, doi:10.1073/pnas.0906182107

David Haig

Transfers and transitions: Parent–offspring conflict, genomic imprinting, and the evolution of human life history

PNAS 2010 107:1731–1735; published online before print August 4, 2009, doi:10.1073/pnas.0904111106

Maurício Carneiro and Daniel L. Hartl

Adaptive landscapes and protein evolution

PNAS 2010 107:1747–1751; published online before print September 30, 2009, doi:10.1073/pnas.0906192106

Andrew P. Feinberg and Rafael A. Irizarry

Evolution in Health and Medicine Sackler Colloquium: Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease

PNAS 2010 107:1757–1764; published online before print December 22, 2009, doi:10.1073/pnas.0906183107

Claudia M. B. Carvalho, Feng Zhang, and James R. Lupski

Genomic disorders: A window into human gene and genome evolution

PNAS 2010 107:1765–1771; published online before print January 13, 2010, doi:10.1073/pnas.0906222107

A. H. Bittles and M. L. Black

Consanguinity, human evolution, and complex diseases

PNAS 2010 107:1779–1786; published online before print September 23, 2009, doi:10.1073/pnas.0906079106


Randolph M. Nesse, Carl T. Bergstrom, Peter T. Ellison, Jeffrey S. Flier, Peter Gluckman, Diddahally R. Govindaraju, Dietrich Niethammer, Gilbert S. Omenn, Robert L. Perlman, Mark D. Schwartz, Mark G. Thomas, Stephen C. Stearns, and David Valle

Evolution in Health and Medicine Sackler Colloquium: Making evolutionary biology a basic science for medicine

PNAS 2010 107:1800–1807; published online before print November 16, 2009, doi:10.1073/pnas.0906224106

Gülüm Kosova, Mark Abney, and Carole Ober

Heritability of reproductive fitness traits in a human population

PNAS 2010 107:1772–1778; published online before print October 12, 2009, doi:10.1073/pnas.0906196106

Sean G. Byars, Douglas Ewbank, Diddahally R. Govindaraju, and Stephen C. Stearns

Natural selection in a contemporary human population

PNAS 2010 107:1787–1792; published online before print October 26, 2009, doi:10.1073/pnas.0906199106

David Houle

Numbering the hairs on our heads: The shared challenge and promise of phenomics

PNAS 2010 107:1793–1799; published online before print October 26, 2009, doi:10.1073/pnas.0906195106

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1 Comment

  1. John Torday on December 9, 2010 at 3:17 pm

    It is important that the scientific community be made aware of the concept of evolution and medicine. However, until evolution science is reduced to cell-molecular mechanisms, it will not be effectively disseminated or tested experimentally. In a soon-to-be-published book, entitled Evolutionary Biology, Cell-Cell Communication, and Complex Disease (Wiley-Blackwell), we demonstrate how evolutionary biology is a continuum from cell-molecular development to homeostasis and disease. By seeing evolution from a cell-centric perspective, from unicellular to multicellular organisms, as cell-cell communication, genetics and phenotypes are mechanistically integrated, informative and predictive.

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