Amino Acid Gymnastics and the Evolution of Influenza Virus Resistance to Oseltamivir
Posted in Genetics, Infection, Pharmacology, Phylogeny, Trade-offs, evolutionary medicine on Jun 23rd, 2010
In previous posts, I discussed, respectively, the use of selection to generate an antibody of potential value in treating influenza A virus infections (1) and the relevance of protein dynamics to the evolution of protein function (2). A recent paper in Science (3) offers evidence suggesting that internal protein dynamics play a crucial role in [...]
