Genes essential to the immune system that are “entrusted” to microbial “Old Friends”
Posted in Article review, Autoimmune disease, Defenses, Ideas, Infection, evolutionary medicine on Jul 21st, 2008
In 2005 Sarkis Mazmanian and colleagues showed that a single polysaccharide from an intestinal commensal, Bacteroides fragilis, could largely correct the subnormal and functionally distorted development of the immune system that occurs in germ-free mice (Mazmanian et al. 2005). More recently they have shown, using three different models of intestinal inflammation, that the same polysaccharide, [...]
