Among human pathogens, Streptococcus pneumoniae holds an especially prominent place in the history of biomedical investigation. Griffith (1928) described the transforming principle, a soluble substance released by dead, virulent pneumococci that could render...
In the April 16, 2010, issue of Cell Jon McClellan and Mary-Claire King published a commentary that addressed the nature of the genetic variation that accounts for common human diseases, an issue of profound importance in evolutionary medicine. The authors also...