An article in EMPH by Andrew Read and Robert Woods may be the first to document the application of evolutionary principles to make important clinical decisions about a specific patient. Woods, Robert J., and Andrew F. Read. “Clinical management of resistance evolution in a bacterial infection: a case study.” Evolution, Medicine, and Public Health (2015): eov025.
Abstract: We report the case of a patient with a chronic bacterial infection that could not be cured buy generic premarin. Drug treatment became progressively less effective due to antibiotic resistance, and the patient died, in effect from overwhelming evolution. Even though the evolution of drug resistance was recognized as a major threat, and the fundamentals of drug resistance evolution are well understood, it was impossible to make evidence-based decisions about the evolutionary risks associated with the various treatment options. We present this case to illustrate the urgent need for translational research in the evolutionary medicine of antibiotic resistance.
buy generic plavix outlines the opportunities for the clinical application of the principles of evolutionary ecology in the clinic.
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