http://emph.oxfordjournals.org/content/2015/1?etoc

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Editorial
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Editorial: What we aim for
Stephen C. Stearns
Evol Med Public Health 2015 2015: 122
http://emph.oxfordjournals.org/content/2015/1/122.extract?etoc

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Original Research Articles
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Post-term birth as a response to environmental stress: The case of
September 11, 2001
Claire E.  Margerison-Zilko, Julia M. Goodman, Elizabeth Anderson, Alison
Gemmill, and Ralph A. Catalano
Evol Med Public Health 2015 2015: 13-20
http://emph.oxfordjournals.org/content/2015/1/13.abstract?etoc

Illness in breastfeeding infants relates to concentration of lactoferrin
and secretory Immunoglobulin A in mother’s milk
Alicia A. Breakey, Katie Hinde, Claudia R. Valeggia, Allison Sinofsky,
and Peter T. Ellison
Evol Med Public Health 2015 2015: 21-31
http://emph.oxfordjournals.org/content/2015/1/21.abstract?etoc

Modern reproductive patterns associated with estrogen receptor positive
but not negative breast cancer susceptibility
C. Athena Aktipis, Bruce J. Ellis, Katherine K. Nishimura, and Robert A.
Hiatt
Evol Med Public Health 2015 2015: 52-74
http://emph.oxfordjournals.org/content/2015/1/52.abstract?etoc
It has long been accepted that modern reproductive patterns are likely
contributors to breast cancer susceptibility because of their influence
on hormones such as estrogen and the importance of these hormones in
breast cancer. We found that modern reproductive patterns of later age of
first birth and lower parity were associated with ER-positive but not
ER-negative breast cancer. Thus, the evolutionary mismatch hypothesis for
breast cancer can account for ER-positive breast cancer susceptibility
but not ER-negative breast cancer. buy levaquin 500mg

Divergent and convergent evolution in metastases suggest treatment
strategies based on specific metastatic sites
Jessica J. Cunningham, Joel S. Brown, Thomas L. Vincent, and Robert A.
Gatenby
Evol Med Public Health 2015 2015: 76-87
http://emph.oxfordjournals.org/content/2015/1/76.abstract?etoc
Cancer cells, although maximally fit at their primary site, typically
have lower fitness on the adaptive landscapes offered by the metastatic
sites due to organ-specific variations in mesenchymal properties and
signaling pathways. Clinically evident metastases will exhibit
time-dependent divergence from the phenotypic mean of the primary
population as the tumor cells evolve and adapt to their new
circumstances. In contrast, tumors from different primary sites evolving
on identical metastatic adaptive landscapes exhibit phenotypic
convergence so that, for example, metastases in the liver from different
primary tumors will evolve toward similar adaptive phenotypes. The
combination of evolutionary divergence from the primary cancer phenotype
and convergence towards similar adaptive strategies in the same tissue
cause significant variations in treatment responses particularly for
highly targeted therapies. This suggest that optimal therapies for
disseminated cancer must take into account the site(s) of metastatic
growth as well as the primary organ. buy plavix 75mg

Elevated levels of adaption in Helicobacter pylori genomes from Japan; a
link to higher incidences of gastric cancer?
Maria Juliana Soto-Girón, Oscar E. Ospina, and Steven Edward Massey
Evol Med Public Health 2015 2015: 88-105
http://emph.oxfordjournals.org/content/2015/1/88.abstract?etoc

Adaptive learning can result in a failure to profit from good conditions:
implications for understanding depression
Pete C. Trimmer, Andrew D. Higginson, Tim W. Fawcett, John M. McNamara,
and Alasdair I. Houston
Evol Med Public Health 2015 2015: 123-135
http://emph.oxfordjournals.org/content/2015/1/123.abstract?etoc

Why did children grow so well at hard times? The ultimate importance of
pathogen control during puberty
Peeter Hõrak and Markus Valge
Evol Med Public Health 2015 2015: 167-178
http://emph.oxfordjournals.org/content/2015/1/167.abstract?etoc
Europeans became larger and smarter throughout the 20th century despite
the temporally worsening access to nutrients during and after WWII.
Measurements of Estonian adolescent girls born between 1938-1953 suggest
that a reduction of disease burden during puberty drives secular trends,
overriding the adverse effects of resource shortage at birth. buy nexium 20mg

The evolution of capture myopathy in hooved mammals: a model for human
stress cardiomyopathy?
Daniel T. Blumstein, Janet Buckner, Sajan Shah, Shane Patel, Michael E.
Alfaro, and Barbara Natterson-Horowitz
Evol Med Public Health 2015 2015: 195-203
http://emph.oxfordjournals.org/content/2015/1/195.abstract?etoc

A genetic model of the effects of insecticide-treated bed nets on the
evolution of insecticide-resistance
Philip L. G. Birget and Jacob C. Koella
Evol Med Public Health 2015 2015: 205-215
http://emph.oxfordjournals.org/content/2015/1/205.abstract?etoc
Insecticides used for malaria control protect communities by killing
larval or adult mosquitoes, and offer personal protection by repelling
mosquitoes. We show that using the insecticides as larvicides selects for
resistance more rapidly that using them against adult mosquitoes, and
that their repellency can delay considerably the evolution of resistance.

Near full-length HIV type 1M genomic sequences from Cameroon: Evidence of
early diverging under-sampled lineages in the country
Marcel Tongo, Jeffrey R. Dorfman, Melissa-Rose Abrahams, Eitel
Mpoudi-Ngole, Wendy A. Burgers, and Darren P. Martin
Evol Med Public Health 2015 2015: 254-265
http://emph.oxfordjournals.org/content/2015/1/254.abstract?etoc

Effects of local extrinsic mortality rate, crime and sex ratio on
preventable death in Northern Ireland
Caroline Uggla and Ruth Mace
Evol Med Public Health 2015 2015: 266-277
http://emph.oxfordjournals.org/content/2015/1/266.abstract?etoc
Variation in preventable death can be understood from an evolutionary
life history perspective. However, previous studies have failed to
isolate ecological effects on preventable death. We use population-wide
Census data from Northern Ireland and find that extrinsic mortality rate
and crime, but not sex ratio, impacts on male preventable death.

Viral meningitis epidemics and a single, recent, recombinant and
anthroponotic origin of swine vesicular disease virus
Christian A. W. Bruhn, Sandra C. Abel  Nielsen, Jose Alfredo Samaniego,
Jemma Wadsworth, Nick J. Knowles, and M. Thomas P. Gilbert
Evol Med Public Health 2015 2015: 289-303
http://emph.oxfordjournals.org/content/2015/1/289.abstract?etoc
Swine vesicular disease, an important viral disease affecting domestic
pigs, is shown to have a single and recent origin in humans, leading us
closer to a full understanding of the sudden emergence of this enigmatic
veterinary disease, and exemplifying the sometimes overlooked risk of
human to animal disease transfers.

Links among inflammation, sexual activity and ovulation: Evolutionary
trade-offs and clinical implications
Tierney K. Lorenz, Carol M. Worthman, and Virginia J. Vitzthum
Evol Med Public Health 2015 2015: 304-324
http://emph.oxfordjournals.org/content/2015/1/304.abstract?etoc
Inflammation in healthy sexually active women decreased at midcycle,
around ovulation, which may have evolved to promote conception.

Inheritance of the 8.1 ancestral haplotype in recurrent pregnancy loss
Astrid M. Kolte, Henriette S. Nielsen, Rudi Steffensen, Bernard Crespi,
and Ole B. Christiansen
Evol Med Public Health 2015 2015: 325-331
http://emph.oxfordjournals.org/content/2015/1/325.abstract?etoc
A segment of DNA called the 8.1 ancestral haplotype is hypothesized to
cause fetal loss due to a ‘selfish gene’ effect. The hypothesis was not
supported, although the haplotype tended to be inherited more often than
expected among girls (p=0.11) in a study of 110 mother-child pairs.
Further studies are warranted.

Effects of wildfire disaster exposure on male birth weight in an
Australian population
M. H. O’Donnell and A. M. Behie
Evol Med Public Health 2015 2015: 344-354
http://emph.oxfordjournals.org/content/2015/1/344.abstract?etoc

Childhood family disruption and adult height: is there a mediating role
of puberty?
Paula Sheppard, Justin R. Garcia, and Rebecca Sear
Evol Med Public Health 2015 2015: 332-342
http://emph.oxfordjournals.org/content/2015/1/332.abstract?etoc

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Clinical Briefs
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Evolution and Diversity of the Human Leukocyte Antigen(HLA)
Peter V. Markov and Oliver G. Pybus
Evol Med Public Health 2015 2015: 1
http://emph.oxfordjournals.org/content/2015/1/1.extract?etoc

Lower back pain
Eric R. Castillo and Daniel E. Lieberman
Evol Med Public Health 2015 2015: 2-3
http://emph.oxfordjournals.org/content/2015/1/2.extract?etoc

HIV vaccine development and broadly neutralizing antibodies
Neil S. Greenspan, Ashutosh K. Sheth, and Vilok Desai
Evol Med Public Health 2015 2015: 75
http://emph.oxfordjournals.org/content/2015/1/75.extract?etoc

Iron restriction
John H. McCullough
Evol Med Public Health 2015 2015: 149
http://emph.oxfordjournals.org/content/2015/1/149.extract?etoc

Breastfeeding and infant growth
Amber Gigi Hoi and Luseadra McKerracher
Evol Med Public Health 2015 2015: 150-151
http://emph.oxfordjournals.org/content/2015/1/150.extract?etoc

Horizontal Gene Transfer
Alita R. Burmeister
Evol Med Public Health 2015 2015: 193-194
http://emph.oxfordjournals.org/content/2015/1/193.extract?etoc

Resistance to cellular HIV infection
Alice M. Clomegah and Stephen J. Chapman
Evol Med Public Health 2015 2015: 204
http://emph.oxfordjournals.org/content/2015/1/204.extract?etoc

Osteoporosis
Ian J. Wallace, Clinton T. Rubin, and Daniel E. Lieberman
Evol Med Public Health 2015 2015: 343
http://emph.oxfordjournals.org/content/2015/1/343.extract?etoc

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Reviews
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Limits to compensatory adaptation and the persistence of antibiotic
resistance in pathogenic bacteria
R. Craig MacLean and Tom Vogwill
Evol Med Public Health 2015 2015: 4-12
http://emph.oxfordjournals.org/content/2015/1/4.abstract?etoc

Papillomaviruses: Viral evolution, cancer and evolutionary medicine
Ignacio G. Bravo and Marta Félez-Sánchez
Evol Med Public Health 2015 2015: 32-51
http://emph.oxfordjournals.org/content/2015/1/32.abstract?etoc

Is preterm birth a human-specific syndrome?
Julie Baker Phillips, Patrick Abbot, and Antonis Rokas
Evol Med Public Health 2015 2015: 136-148
http://emph.oxfordjournals.org/content/2015/1/136.abstract?etoc

Evolutionary decay and the prospects for long-term disease intervention
using engineered insect vectors
J. J. Bull
Evol Med Public Health 2015 2015: 152-166
http://emph.oxfordjournals.org/content/2015/1/152.abstract?etoc

Microbiology and ecology are vitally important to premedical curricula
Val H. Smith, Rebecca J. Rubinstein, Serry Park, Libusha Kelly, and Vanja
Klepac-Ceraj
Evol Med Public Health 2015 2015: 179-192
http://emph.oxfordjournals.org/content/2015/1/179.abstract?etoc

Diametrical diseases reflect evolutionary-genetic tradeoffs: Evidence
from psychiatry, neurology, rheumatology, oncology and immunology
Bernard J. Crespi and Matthew C. Go
Evol Med Public Health 2015 2015: 216-253
http://emph.oxfordjournals.org/content/2015/1/216.abstract?etoc

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Commentary
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Milk bioactives may manipulate microbes to mediate parent–offspring
conflict
Cary R. Allen-Blevins, David A. Sela, and Katie Hinde
Evol Med Public Health 2015 2015: 106-121
http://emph.oxfordjournals.org/content/2015/1/106.abstract?etoc

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Correspondence
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Capture myopathy in hooved mammals and human Takotsubo syndrome
John E. Madias
Evol Med Public Health 2015 2015: 278-279
http://emph.oxfordjournals.org/content/2015/1/278.extract?etoc

A clinical research pathway towards developing new insights into
cardiomyopathy
Daniel T. Blumstein, Janet Buckner, Sajan Shah, Shane Patel, Michael E.
Alfaro, and Barbara Natterson-Horowitz
Evol Med Public Health 2015 2015: 280
http://emph.oxfordjournals.org/content/2015/1/280.extract?etoc

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Case Studies
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Clinical management of resistance evolution in a bacterial infection: A
case study
Robert J. Woods and Andrew F. Read
Evol Med Public Health 2015 2015: 281-288
http://emph.oxfordjournals.org/content/2015/1/281.abstract?etoc
This chronic bacterial infection evolved extensive resistance, killing
the patient. Evolutionary science is insufficiently developed to better
manage such life-threatening evolution.

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