Iron is a critical metal for essential cellular processes, such as respiration, in both human and microbial cells. Thus, in the context of infection, iron is a high-value cellular commodity and an evolutionist might reasonably expect a metallic tug-of-war between...
Peter and Rosemary Grant have been responsible for what must be among the longest-running continuous field studies in evolutionary biology (2011). It will reach forty years in 2013. In this work, the Grants closely follow multiple species of finches on the Galápagos...
Evolutionary processes, and specifically selection-based mechanisms, have long served to inspire in vitro methods for generating proteins and nucleic acids that mediate functions of interest. Examples going back two decades include the development of phage...
In the early years of the last century, Paul Ehrlich coined the term “magic bullet” to indicate a therapeutic agent that targeted an infectious agent or tumor with exquisite specificity (Schwartz, 2004). He was inspired by his work with antibodies to imagine a future...