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Category Archive for 'evolutionary medicine'

By Maiara Marx Luz Fiusa, Marco Antonio Carvalho-Filho1, Joyce M Annichino-Bizzacchi and Erich V De Paula Published in BMC Med. 2015 May 6;13(1):105. doi: 10.1186/s12916-015-0327-2. (open access) Abstract BACKGROUND: Coagulation and innate immunity have been linked together for at least 450 million years of evolution. Sepsis, one of the world’s leading causes of death, is probably the condition in which […]

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Evolutionary Medicine  Stephen C. Stearns, the Edward P Bass Professor of Ecology and Evolutionary Biology at Yale University Ruslan Medzhitov, the David W. Wallace Professor of Immunobiology at Yale University School of Medicine and an Investigator with the Howard Hughes Medical Institute This textbook is intended for use in undergraduate, graduate, medical school, and continuing medical education […]

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In an EMR commentary (http://evmedreview.com/?p=1644) from March two years ago, I discussed issues related to the functional classification of genomic DNA sequences that arose in the context of claims from the ENCODE (ENCyclopedia Of DNA Elements) consortium.  A particular focus of that piece was an article by Graur and colleagues (2013) that offered an often […]

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Travel support for this meeting is available from Tri-CEM, the new evolutionary medicine Center at Duke University directed by Charlie Nunn. The abstract deadline is NOW! Evolutionary Medicine Conference: Interdisciplinary Perspectives on Human Health and Disease July 30 – August 1, 2015 Institute of Evolutionary Medicine (IEM) University of Zurich, Switzerland This international conference will […]

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Divergent and convergent evolution in metastases suggest treatment strategies based on specific metastatic sites By Jessica J. Cunningham, Joel S. Brown, Thomas L. Vincent, and Robert A. Gatenby In Evol Med Public Health published 20 March 2015, 10.1093/emph/eov006   (open access) Abstract: Cancer cells, although maximally fit at their primary site, typically have lower fitness on […]

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Last month, Murphy and colleagues (Cell, 2015) published a fascinating report about a patient with an immunodeficiency syndrome that underwent spontaneous resolution.  The mechanism for this remarkable outcome points to the importance of somatic cell selection and evolution in the origins, pathogenesis, and most dramatically in this case, elimination of disease.

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The winners of the Gil Omenn Prize for 2013 and 2014 received recognition and their $5000 prize money at the inaugural meeting of the International Society for Evolution, Medicine & Public Health. Gil Omenn has just announced a major donation to the Society that will sustain the prize for at least three more years.  The prize is […]

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The final program for the inaugural meeting of the International Society for Evolution, Medicine, & Public Health  is now online.  All talks on Thursday March 19 will be live streamed at http://www.ustream.tv/asutv The time zone is the same as California, so 3 hours earlier that EDT, and 7 hours earlier than London UK.  

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The abstract deadline for the “Evolutionary Medicine Conference: Interdisciplinary Perspectives on Human Health and Disease” (Juli 30-August 1 2015 in Zurich, Switzerland) is approaching now: – Abstract Deadline: March 30, 2015 – Early registration Deadline: May 31, 2015 Find all relevant information (abstract submission, registration, accommodation, etc.) on our official conference webpage:http://www.iem.uzh.ch/evolmedconf2015.html Please get in contact with us […]

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The Gilbert S. Omenn Prize is awarded by the International Society for Evolution, Medicine, and Public Health for best article published each year on a topic related to evolution in the context of medicine and public health.  The prize for 2014 goes to, “Escape from bacterial iron piracy through rapid evolution of transferrin” by Matthew […]

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Carina Schlebusch and colleagues just published an article in Molecular Biology and Evolution demonstrating human adaptation to the locally high arsenic levels in groundwater in the Argentine Andes. This work is the first to show a genetic adaptation that allows the detoxification of a environmental toxin (arsenic) in humans. Title: Human adaptation to arsenic-rich environments […]

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Carcinomas of the prostate are the most common cancers affecting men and a leading cause of male cancer deaths in the United States (CDC web site, Cancer Prevention and Control).  Given the unique association of the prostate with males, it makes sense that prosate carcinoma cells are often dependent for continued growth and proliferation on […]

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Rodríguez JA, Marigorta UM, Navarro A. Integrating genomics into evolutionary medicine. Curr. Opin. Genet. Dev. 2014;29:97-102 Also see an interesting blog post on Paleophile Abstract: The application of the principles of evolutionary biology into medicine was suggested long ago and is already providing insight into the ultimate causes of disease. However, a full systematic integration […]

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An Evolutionary Medicine Approach to Understanding Factors That Contribute to Chronic Obstructive Pulmonary Disease  By Aoshiba K(1), Tsuji T, Itoh M, Yamaguchi K, Nakamura H. Tokyo Medical University Ibaraki Medical Center, Inashiki, Japan. Published in Respiration. 2015 Feb 10. [Epub ahead of print] (Not open access) Although many studies have been published on the causes […]

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Dr Darwin  an article By Timothy Gower, Art by Tim O’Brien  published in Proto, Winter, 2015   (open access) Can a refresher course in the laws of natural selection help doctors better understand human health and illness? ANDREW READ RECENTLY SPENT SIX MONTHS on the wards at the University of Michigan Medical Center, observing doctors who treat infectious disease. He […]

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The Infectious Disease Evolution Across Scales RCN seeks applicants for research exchanges and workshops sporozoites The NSF-funded Research Coordination Network (RCN) focusing on infectious disease evolution is excited to fund several research exchanges as well as annual workshops. The RCN is focused on integrating new theoretical and empirical tools for the study of infectious diseases across […]

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The deadlines for mini-symposia suggestions (Feb 16) and for standard abstracts (Mar 30) are approaching! Clicking the picture to the right for full info Evolutionary Medicine Conference: Interdisciplinary Perspectives on Human Health and Disease July 30 – August 1, 2015 Institute of Evolutionary Medicine (IEM)   University of Zurich, Switzerland This international conference will bring together […]

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George C. Williams The International Society for Evolution, Medicine and Public Health is proud to announce the launch of the George C. Williams Prize. The $5,000 Prize will be awarded to the first author of the most significant article published in 2015 in the Society’s flagship journal, Evolution, Medicine and Public Health. Oxford University Press publishes the journal […]

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According to estimates by the World Health Organization, in 2013 on the order of 35 million people were infected with HIV worldwide (http://www.who.int/gho/hiv/en/).  Globally, about 1.5 million people are believed to have died from AIDS-related diseases in that year.  Substantial, although perhaps not insurmountable, obstacles to the development of a highly effective vaccine for HIV-1 […]

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By  Ignacio G. Bravo and Marta Félez-Sánchez   Evol Med Public Health published 28 January 2015, 10.1093/emph/eov003 http://emph.oxfordjournals.org/content/early/2015/01/28/emph.eov003.abstract?papetoc Abstract:   Papillomaviruses (PVs) are a numerous family of small dsDNA viruses infecting virtually all mammals. PVs cause infections without triggering a strong immune response, and natural infection provides only limited protection against reinfection. Most PVs are part and […]

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