A fascinating article in Nature finds positive selection for several alleles that protected against Yersinia pestis during the plague of 1346-1350 in Europe; they also increase the risk of autoimmune disease. Klunk, J., et al. (2022). Evolution of immune genes is...
This delightful Perspective provides an exciting overview of how human innate immunity is based on bacterial systems, pointing to common ancestry, and not to convergent evolution. Wein, T., Sorek, R. Bacterial origins of human cell-autonomous innate immune...
