Immunoselective Subversion of Therapy for Myeloid Cancer

In a couple of previous posts I wrote about investigators who harnessed concepts derived from the study of evolution to generate therapeutic agents, in one case for a viral infection (2009a) and in another case for cancer (2009b). Below, I discuss a study from 2009...

Reflection on Detection of Positive Selection

According to an article, in 2005, by Nicholas Wade of The New York Times, the notion that human evolution had effectively stalled in the distant past (i.e., 50,000 years ago) had been widely accepted.  As recently as 2007, the eminent Harvard psychologist, author, and...

Therapeutic Selection

It has been roughly fifty years since the humoral immune response was first conceived of as a compelling example of evolution via selection of individual cells on a time scale that is short relative to standard organismal evolution (Talmage, 1957, Burnet, 1957;...