Can hitchhiking account for some deleterious alleles?

Many evolutionary models of genetic disease postulate hitchhiking of deleterious alleles adjacent to advantageous alleles.  This paper offers a quantitative analysis of the likely importance of such effects, and concludes with an intriguing speculation about selection...

Evolution and Medicine Course Materials Available

Complete materials for the August 2011 CME course at Mt Desert Island Biological Laboratories  Evolutionary Foundations for Medicine and Public Health are now available on the web. Forty participants joined eight faculty for a memorable week. If you would like advance...

The Self-ish Cell: Cancer’s emerging evolutionary paradigm

The Self-ish Cell: Cancer’s emerging evolutionary paradigm A report from the First International Biannual Evolution and Cancer Conference C. Athena Aktipis1,3 and Carlo C. Maley1,2 1 Center for Evolution and Cancer Helen Diller Family Comprehensive Cancer Center 2...