Evolutionary Genetics of Coronary Heart Disease

Circulation. 2009;119:459-467 doi: 10.1161/CIRCULATIONAHA.108.809970 Keyue Ding, PhD; Iftikhar J. Kullo, MD Nothing in biology makes sense except in the light of evolution.1— —Theodosius Dobzhanksy, 1973 No biological problem is solved until both the proximate...

The disappearing human microbiota

What are the consequences of the disappearing human microbiota? by Martin J. Blaser and Stanley Falkow in Nature Reviews Microbiology   doi:10.1038/nrmicro2245 Who are we? From prions and organelles up through neighborhoods and nation-states, we are groups...

Numbering the hairs on our heads: Phenomics rising

Numbering the hairs on our heads: The shared challenge and promise of phenomics PNAS  full text available open access doi:10.1073/pnas.0906195106 by David Houle Abstract Evolution and medicine share a dependence on the genotype–phenotype map. Although genotypes...

Groups say med school training must evolve

Nature Medicine 15, 1338 (2009) doi:10.1038/nm1209-1338a By Daniel Cressey Introduction Medical training must adapt to include coursework covering evolutionary biology, according to a group of leading researchers. Momentum for such change seems to be building. This...

Leprosy, kuru and co-evolution in human history

Diseases, human history and co-evolution with pathogens Peter Gluckman and Tatjana Buklijas Liggins Institute, The University of Auckland, New Zealand Leprosy and kuru may at first glance seem to be diseases with little in common, except, perhaps, their large...