Genetic diversity: Driving cancer evolution

Genetic diversity: Driving cancer evolution

There are two related and interesting articles on cancer evolution in a recent edition of eLife. The first is a commentary by Devon M Fitzgerald and Susan M Rosenberg, of the Baylor College of Medicine, on a paper in the same issue  titled “TGF-β reduces DNA...
Is atherosclerosis a modern disease after all?

Is atherosclerosis a modern disease after all?

What factors should we blame most for the continuing pandemic of heart and artery disease throughout the Western world? The argument has endured more twists and turns than California Route 1. For years, the diet cholesterol hypothesis has held sway, with added blame...
How cancer escapes chemotherapy

How cancer escapes chemotherapy

This is a heads up for a very useful essay, written by Mel Greaves, for The Darwin Cancer Blog – a blog dedicated to commenting on evolutionary approaches to cancer. In this essay, titled “Ways of Escape”, Greaves draws a number of comparisons...

More misery for the amyloid hypothesis

Further to our feature, a few weeks ago, on the state of health of the amyloid hypothesis – the dominant hypothesis to explain Alzheimer’s disease – comes news of yet another abandoned trial. This time the company is Merck and the drug under test is...