Immunoselective Subversion of Therapy for Myeloid Cancer

In a couple of previous posts I wrote about investigators who harnessed concepts derived from the study of evolution to generate therapeutic agents, in one case for a viral infection (2009a) and in another case for cancer (2009b). Below, I discuss a study from 2009...

Sanitizing the hygiene hypothesis (Workshop Report)

Sanitizing the hygiene hypothesis: Health lessons from human co-evolution with microorganisms Report from a Workshop led by Kathleen Barnes, Department of Medicine, Johns Hopkins University and Erika von Mutius, Professor of Pediatrics, University Children’s...

Therapeutic Selection

It has been roughly fifty years since the humoral immune response was first conceived of as a compelling example of evolution via selection of individual cells on a time scale that is short relative to standard organismal evolution (Talmage, 1957, Burnet, 1957;...