The mathematician versus the malignancy
An engaging story about using mathematical models to improve chemotherapy.
By Elie Dolgin
The way in which people receive cancer therapy is pretty much the same as it’s been for decades: researchers determine the highest dose of a drug or treatment that does not cause unacceptable side effects; oncologists then administer that dose to patients on a standard timetable—usually daily tablets for oral chemotherapeutics and other pill-based regimens, infusions on a weekly schedule for injectable drugs and Monday-through-Friday treatments for radiation therapy.
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Almost all current cancer therapies are given this way. And although the approach has undoubtedly extended countless patients’ lives, given that more than $80 billion is spent on cancer care in the US alone, it’s worth asking: are these schedules really yielding the best results for patients? And could alternative timetables produce better outcomes?
Franziska Michor hopes to answer these questions. Read more here